Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press111210.36691/RJA1112ArticlesСтатьиβDEFENZINY: SVOYSTVA I FUNKTsIIβДЕФЕНЗИНЫ: СВОЙСТВА И ФУНКЦИИBudikhinaA SБудихинаА С

ГНЦ «Институт иммунологии ФМБА России», Москва

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ГНЦ «Институт иммунологии ФМБА России», Москва

ГНЦ «Институт иммунологии ФМБА России», Москва1506200853NO3 (2008)№3 (2008)152111032020Copyright ©; 2008, Pharmarus Print MediaCopyright ©; 2008, Фармарус Принт Медиа2008Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/1112

Продукция природных катионных пептидов - важный механизм врожденного иммунитета человека. βДефензины человека принадлежат семейству катионных трисульфидсодержащих микробоцидных пептидов. Кроме прямых антимикробных функций, βдефензины играют множественную роль как ме диаторы воспаления, влияют на хемотаксис, обладают иммуномодулирующей, цитотоксической и др. активностями. Более того, βдефензины рассматриваются как лекарства нового поколения, которые мож но будет использовать как антибактериальные средства, как модуляторы воспаления и при терапии рака. Кроме того, βдефензины играют важную воль в аутоиммунных патологиях

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