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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Allergy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Allergy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский Аллергологический Журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1810-8830</issn><issn publication-format="electronic">2686-682X</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1078</article-id><article-id pub-id-type="doi">10.36691/RJA1078</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Has the first generation of antihistamines any advantages?</article-title><trans-title-group xml:lang="ru"><trans-title>К вопросу о «преимуществах» антигистаминных препаратов первого поколения</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Il'ina</surname><given-names>N I</given-names></name><name xml:lang="ru"><surname>Ильина</surname><given-names>Н И</given-names></name></name-alternatives><bio xml:lang="ru"><p>ФГБУ ГНЦ «Институт иммунологии ФМБА России»</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pavlova</surname><given-names>K S</given-names></name><name xml:lang="ru"><surname>Павлова</surname><given-names>К С</given-names></name></name-alternatives><bio xml:lang="ru"><p>ФГБУ ГНЦ «Институт иммунологии ФМБА России»</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kurbacheva</surname><given-names>Oksana Mikhaylovna</given-names></name><name xml:lang="ru"><surname>Курбачёва</surname><given-names>Оксана Михайловна</given-names></name></name-alternatives><bio xml:lang="ru"><p>ФГБУ ГНЦ «Институт иммунологии ФМБА России»</p></bio><email>Kurbacheva@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Lljina</surname><given-names>N L</given-names></name><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Pavlova</surname><given-names>K S</given-names></name><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Kurbacheva</surname><given-names>O M</given-names></name><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">ФГБУ ГНЦ «Институт иммунологии ФМБА России»</institution></aff></aff-alternatives><aff id="aff2"><institution></institution></aff><pub-date date-type="pub" iso-8601-date="2009-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2009</year></pub-date><volume>6</volume><issue>3</issue><issue-title xml:lang="en">NO3 (2009)</issue-title><issue-title xml:lang="ru">№3 (2009)</issue-title><fpage>78</fpage><lpage>82</lpage><history><date date-type="received" iso-8601-date="2020-03-10"><day>10</day><month>03</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2009, Pharmarus Print Media</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2009, Фармарус Принт Медиа</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="en">Pharmarus Print Media</copyright-holder><copyright-holder xml:lang="ru">Фармарус Принт Медиа</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2011-09-15"/></permissions><self-uri xlink:href="https://rusalljournal.ru/raj/article/view/1078">https://rusalljournal.ru/raj/article/view/1078</self-uri><abstract xml:lang="en"><p/></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>anthihistamines</kwd><kwd>side effects</kwd><kwd>loratadine (klarotadine)</kwd><kwd>allergic rhinitis</kwd><kwd>bronchial asthma</kwd><kwd>atopic dermatitis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>антигистаминные</kwd><kwd>побочные эффекты</kwd><kwd>лоратадин (Кларотадин®)</kwd><kwd>аллергический ринит</kwd><kwd>бронхиальная астма</kwd><kwd>атопический дерматит</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 Update. 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