Russian Journal of AllergyRussian Journal of AllergyРоссийский Аллергологический Журнал1810-88302686-682XPublishing House ABV Press101510.36691/RJA1015ArticlesСтатьиChitin and chitinases in allergic reactionsХитин и хитиназы при аллергических реакцияхKulikovS NКуликовС Н

Казанский научно-исследовательский институт эпидемиологии и микробиологии

TyurinYu AТюринЮ А

Казанский научно-исследовательский институт эпидемиологии и микробиологии

DolbinD AДолбинД А

Казанский научно-исследовательский институт эпидемиологии и микробиологии

FassakhovR SФассаховР С

Казанский научно-исследовательский институт эпидемиологии и микробиологии

KulikovS NTurinIu ADolbinD AFassakhovR SКазанский научно-исследовательский институт эпидемиологии и микробиологии1502200961NO1 (2009)№1 (2009)182310032020Copyright ©; 2009, Pharmarus Print MediaCopyright ©; 2009, Фармарус Принт Медиа2009Pharmarus Print MediaФармарус Принт Медиаhttps://rusalljournal.ru/raj/article/view/1015

Chitin - the structural component of fungal cell wall, arthropodal exoskeleton, microfilarial sheat and egg of helminths. Allergens of this organisms cause allergic diseases. The potential role of chitin in allergic reactions has been discussed. Other studies have suggested that chitin preparations may skew immunity away from T-helper-2-mediated allergic responses. Chitinases, enzymes that can degrade chitin polymer, and chitinase-like proteins might also play an important role in allergic disease pathogenesis.

Хитин - один из компонентов поверхностных структур гельминтов, членистоногих, грибов. Аллергены этих видов организмов часто становятся причиной развития атопических заболеваний у человека. Потенциальная роль хитина в аллергических реакциях активно обсуждается в настоящее время. Специальное внимание обращено на экспериментальные данные об антиаллергическом действии некоторых препаратов на основе хитина и хитозана. В последнее время продемонстрировано участие в аллергических процессах и хитиназ - ферментов, расщепляющих хитиновый полимер, а также хитиназоподобных белков.

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