Drug allergy to folic acid - myth or reality?



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Abstract

Drug allergy is one of the most interesting and complex issues that a doctor of any speciality may encounter in their practice. Accordingly, the study of drug allergies remains a pressing concern in modern medicine, including allergology, taking into account the increase in the number of pharmacological drugs  available on the market, the duration of drug use in global practice, and the development of pharmacotherapy for various nosologies. The main causative drugs of drug hypersensitivity are antibiotics and NSAIDs. Folic acid is a rare trigger of drug allergy. Currently, there are only a few reported cases of drug allergy to folic acid. This article presents a clinical case of immediate-type drug allergy to folic acid, confirmed by in vivo testing.

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About the authors

Yulia М. Klimanova

National Research Center — Institute of Immunology Federal Medical-Biological Agency of Russia

Author for correspondence.
Email: ulklim5@gmail.com
ORCID iD: 0009-0009-1349-7187
SPIN-code: 8867-9448
Russian Federation, Москва

Elena A. Latysheva

National Research Center — Institute of Immunology Federal Medical-Biological Agency of Russia

Email: ealat@mail.ru
ORCID iD: 0000-0002-1606-205X
SPIN-code: 2063-7973

Dr. Sci. (Medicine)

Russian Federation, Moscow

Tatiana N. Myasnikova

National Research Center — Institute of Immunology Federal Medical-Biological Agency of Russia

Email: t_miasnikova@mail.ru
ORCID iD: 0000-0001-8491-195X
SPIN-code: 4684-3112

MD, Cand. Sci. (Med.)

Russian Federation, Moscow

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