The problems of long-term adherence to elimination diets in children with food allergies

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Abstract

In recent years, the challenge of the control and maintenance of nutritional status in patients on an elimination diet for food allergies has got a lot of attention. Due to the possibility of long-term elimination of important food groups without adequate replacement, the high efficiency of this treatment method has been linked with the risk of nutritional deficiency, impaired physical growth, and eating behavior disorders in children. This review takes into account physical growth disorders in children with food allergies due to insufficient intake of micronutrients (vitamins, fatty acids), as well as such behavioral disorders as a distortion of food and taste preferences and food neophobia. We also discuss the problems of artificial mixture choice in children who are in their first year of life, correction of the diet in children over one year of age with micronutrient supplementation, as well as the results of studies on the quality of life of both children with elimination diets and people from their families.

When prescribing an elimination diet, the doctor must constantly monitor the diet and growth indices of the child. It is necessary to take to into account the child’s age, his nutritional requirements, and possible deficiencies of nutrients while planning the diet, as well as determine the necessary and sufficient diet duration.

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About the authors

Evgeny E. Emelyashenkov

National Medical Research Center for Children’s Health

Author for correspondence.
Email: dkswdsman@mail.ru
ORCID iD: 0000-0002-0995-4260
SPIN-code: 7018-6434

Graduate Student

Russian Federation, 2, b. 1, Lomonosovsky prospekt, Moscow, 119991

Svetlana G. Makarova

National Medical Research Center for Children’s Health; Lomonosov Moscow State University

Email: sm27@yandex.ru
ORCID iD: 0000-0002-3056-403X
SPIN-code: 2094-2840

MD, Dr. Sci. (Med.), Professor

Russian Federation, 2, b. 1, Lomonosovsky prospekt, Moscow, 119991; Moscow

Andrei P. Fisenko

National Medical Research Center for Children’s Health

Email: fisenko.ap@nczd.ru
ORCID iD: 0000-0001-8586-7946
SPIN-code: 4397-6291

MD, Dr. Sci. (Med.), Professor

Russian Federation, 2, b. 1, Lomonosovsky prospekt, Moscow, 119991

Nikolay N. Murashkin

National Medical Research Center for Children’s Health; First Sechenov Moscow State Medical University (Sechenov University); Central State Medical Academy of Department of Presidential Affairs

Email: murashkin.nn@nczd.ru
ORCID iD: 0000-0003-2252-8570
SPIN-code: 5906-9724

MD, Dr. Sci. (Med.), Professor

Russian Federation, 2, b. 1, Lomonosovsky prospekt, Moscow, 119991; Moscow; Moscow

Albina A. Galimova

National Medical Research Center for Children’s Health

Email: albina86@yandex.ru
ORCID iD: 0000-0002-6701-3872
SPIN-code: 2960-6185

MD, Junior Research Associate

Russian Federation, 2, b. 1, Lomonosovsky prospekt, Moscow, 119991

Oksana A. Ereshko

National Medical Research Center for Children’s Health

Email: ereshko.oa@nczd.ru
ORCID iD: 0000-0002-1650-652X
SPIN-code: 3893-9946

MD, Cand. Sci. (Med.)

Russian Federation, 2, b. 1, Lomonosovsky prospekt, Moscow, 119991

References

  1. Muraro A, Werfel T, Hoffmann-Sommergruber K, et al.; EAACI Food Allergy and Anaphylaxis Guidelines Group. EAACI food allergy and anaphylaxis guidelines: diagnosis and management of food allergy. Allergy. 2014;69(8):1008–1025. doi: 10.1111/all.12429
  2. Saarinen KM, Pelkonen AS, Makela MJ, Savilahti E. Clinical course and prognosis of cow’s milk allergy are dependent on milk-specific IgE status. J Allergy Clin Immunology. 2005;116(4): 869–875. doi: 10.1016/j.jaci.2005.06.018
  3. Savilahti EM, Savilahti E. Development of natural tolerance and induced desensitization in cow’s milk allergy. Pediatr Allergy Immunol. 2013;24(2):114–121. doi: 10.1111/pai.12004
  4. Schoemaker AA, Sprikkelman AB, Grimshaw KE, et al. Incidence and natural history of challenge-proven cow’s milk allergy in European children ― EuroPrevall birth cohort. Allergy. 2015;70(8):963–972. doi: 10.1111/all.12630
  5. Makarova SG, Galimova AA, Fisenko AP, et al. Markers of cow’s milk allergy persistence: results of a 5-year follow-up. Pediatrics J Named After G.N. Speransky. 2020;99(2):88–95. (In Russ). doi: 10.24110/0031-403X-2020-99-2-88-95
  6. Diagnosis and treatment of cow’s milk protein allergy in infants and young children: practical recommendations. Ed. by A.A. Baranov, L.S. Namazova-Baranova, T.E. Borovik, S.G. Makarova. Moscow: Pediatr; 2014. 48 р. (In Russ).
  7. Pavić I, Kolaček S. Growth of children with food allergy. Horm Res Paediatr. 2017;88(1):91–100. doi: 10.1159/000462973
  8. Jhamnani RD, Levin S, Rasooly M, et al. Impact of food allergy on the growth of children with moderate severe atopic dermatitis. J Allergy Clin Immunol. 2018;141(4):1526–1529.e4. doi: 10.1016/j.jaci.2017.11.056
  9. Tuokkola J, Luukkainen P, Nevalainen J, et al. Eliminating cows’ milk, but not wheat, barley or rye, increases the risk of growth deceleration and nutritional inadequacies. Acta Paediatr. 2017;106(7):1142–1149. doi: 10.1111/apa.13846
  10. Mehta H, Ramesh M, Feuille E, et al. Growth comparison in children with and without food allergies in different demographic populations. J Pediatr. 2014;165(4):842–848. doi: 10.1016/j.jpeds.2014.06.003
  11. Sova C, Feuling MB, Baumler M, et al. Systematic review of nutrient intake and growth in children with multiple IgE-mediated food allergies. Nutr Clin Pract. 2013;28(6):669–675. doi: 10.1177/0884533613505870
  12. Beck C, Koplin J, Dharmage S, et al. Persistent food allergy and food allergy coexistent with eczema is associated with reduced growth in the first 4 years of life. J Allergy Clin Immunol Pract. 2016;4(2):248–256.e3. doi: 10.1016/j.jaip.2015.08.009
  13. Meyer R, de Koker C, Dzubiak R, et al. The impact of the elimination diet on growth and nutrient intake in children with food protein induced gastrointestinal allergies. Clin Transl Allergy. 2016;6:25. doi: 10.1186/s13601-016-0115-x
  14. Meyer R. Nutritional disorders resulting from food allergy in children. Pediatr Allergy Immunol. 2018;29(7):689–704. doi: 10.1111/pai.12960
  15. Flammarion S, Santos C, Guimber D, et al. Diet and nutritional status of children with food allergies. Pediatr Allergy Immunol. 2011;22(2):161–165. doi: 10.1111/j.1399-3038.2010.01028.x
  16. Chatchatee P, Vlieg-Boerstra BJ, Groetch M, et al. International survey on growth indices and impacting factors in children with food allergies. J Hum Nutr Diet. 2019;32(2):175–184. doi: 10.1111/jhn.12610
  17. Maslin K, Grundy J, Glasbey G, et al. Cows’ milk exclusion diet during infancy: is there a long-term effect on children’s eating behaviour and food preferences? Pediatr Allergy Immunol. 2016;27(2):141–146. doi: 10.1111/pai.12513
  18. Galimova AA, Emelyashenkov EE, Makarova SG, et al. Health and growth indices in children with cow’s milk protein allergy depending on oral tolerance development. Med Alphabet. 2020;(24):33–37. (In Russ). doi: 10.33667/2078-5631-2020-24-33-37
  19. Ugolev DA. Food preferences (analysis of the problem from the standpoint of adequate nutrition and trophology). Russian J Gastroenterol Hepatology Coloproctology. 2001;9(4):52–63. (In Russ).
  20. Makarova SG. Substantiation and evaluation of the effectiveness of diet therapy for food allergies in children at different age periods [dissertation abstract]. Moscow; 2008. 38 р. (In Russ).
  21. Maslin K, Grimshaw K, Oliver E, et al. Taste preference, food neophobia and nutritional intake in children consuming a cows’ milk exclusion diet: a prospective study. J Hum Nutr Diet. 2016;29(6): 786–796. doi: 10.1111/jhn.12387
  22. Harris G, Mason S. Are there sensitive periods for food acceptance in infancy? Curr Nutr Rep. 2017;6(2):190–196. doi: 10.1007/s13668-017-0203-0
  23. Hatzmann J, Heymans HS, Ferrer-i-Carbonell A, et al. Hidden consequences of success in pediatrics: parental health-related quality of life–results from the Care Project. Pediatrics. 2008;122(5): e1030–e1038. doi: 10.1542/peds.2008-0582
  24. Foong RX, Meyer R, Godwin H, et al. Parental perception of their child’s quality of life in children with non-immunoglobulin-E- mediated gastrointestinal allergies. Pediatr Allergy Immunol. 2017;28(3):251–256. doi: 10.1111/pai.12689
  25. Roberts G, Vazquez-Ortiz M, Knibb R, et al. EAACI Guidelines on the effective transition of adolescents and young adults with allergy and asthma. Allergy. 2020;75(11):2734–2752. doi: 10.1111/all.14459
  26. Meyer R, Godwin H, Dziubak R, et al. The impact on quality of life on families of children on an elimination diet for Non-immunoglobulin E mediated gastrointestinal food allergies. World Allergy Organ J. 2017;10(1):8. doi: 10.1186/s40413-016-0139-7
  27. Howe L, Franxman T, Teich E, Greenhawt M. What affects quality of life among caregivers of food allergic children? Ann Allergy Asthma Immunol. 2014;113(1):69–74.e2. doi: 10.1016/j.anai.2014.04.016
  28. Warren CM, Gupta RS, Sohn MW, et al. Differences in empowerment and quality of life among parents of children with food allergy. Ann Allergy Asthma Immunol. 2015;114(2):117–125. doi: 10.1016/j.anai.2014.10.025
  29. Lianne S, Sharon T, Elaine H, Edmond SC. Current tools measuring anxiety in parents of food-allergic children are inadequate. Pediatr Allergy Immunol. 2020;31(6):678–685. doi: 10.1111/pai.13260
  30. Mikkelsen A, Borres MP, Bjorkelund C, et al. The Food hypersensitivity famiLyImPact (FLIP) questionnaire ― development and first results. Pediatr Allergy Immunol. 2013;24(6):574–581. doi: 10.1111/pai.12105
  31. Petrovskaya MI, Namazova-Baranova LS, Vinyarskaya IV, Makarova SG. Linguistic Ratification and Evaluation of Psychometric Properties of the Specialized FLIP Questionnaire in Russian for Assessing Quality of Life of a Food-Allergic Child’s Family Members: the First Results. Pediatric Pharmacology. 2015;12(6):651–656. (In Russ). doi: 10.15690/pf.v12i6.1488
  32. Methodical guidelines for the use of amino acid formula. Ed. by L.S. Namazova-Baranova. Russian Union of pediatricians. Moscow: Pediatr; 2020. 104 p. (In Russ).
  33. Hill DJ, Murch SH, Rafferty K, et al. The efficacy of amino acid-based formulas in relieving the symptoms of cow’s milk allergy: a systematic review. Clin Exp Allergy. 2007;37(6):808–822. doi: 10.1111/j.1365-2222.2007.02724.x
  34. Vanderhoof J, Moore N, de Boissieu D. Evaluation of an amino acid-based formula in infants not responding to extensively hydrolyzed protein formula. J Pediatr Gastroenterol Nutr. 2016;63(5):531–533. doi: 10.1097/MPG.0000000000001374
  35. NICE clinical guideline 116. Food allergy in children and young people. Diagnosis and assessment of food allergy in children and young people in primary care and community settings. National Institute for Health and Clinical Excellence; 2011. Available from: https://www.nice.org.uk/guidance/cg116/evidence/full-guideline-136470061. Accessed: 25.04.2022.
  36. Koletzko S, Niggemann B, Arato A, et al. Diagnostic approach and management of cow’s-milk protein allergy in infants and children: ESPGHAN GI Committee practical guidelines. J Pediatr Gastroenterol Nutr. 2012;55(2):221–229. doi: 10.1097/MPG.0b013e31825c9482
  37. Sicherer SH, Noone SA, Koerner CB, et al. Hypoallergenicity and efficacy of an amino acid-based formula in children with cow’s milk and multiple food hypersensitivities. J Pediatr. 2001;138(5):688–693. doi: 10.1067/mpd.2001.113007
  38. Meyer R, Groetch M, Venter C. When should infants with cow’s milk protein allergy use an amino acid formula? A practical guide. J Allergy Clin Immunol Pract. 2018;6(2):383–399. doi: 10.1016/j.jaip.2017.09.003
  39. Christie L, Hine RJ, Parker JG, Burks W. Food allergies in children affect nutrient intake and growth. J Am Diet Assoc. 2002;102(11):1648–1651. doi: 10.1016/s0002-8223(02)90351-2
  40. Noimark L, Cox HE. Nutritional problems related to food allergy in childhood. Pediatr Allergy Immunol. 2008;19(2):188–195. doi: 10.1111/j.1399-3038.2007.00700.x
  41. Fox AT, Du TG, Lang A, Lack G. Food allergy as a risk factor for nutritional rickets. Pediatr Allergy Immunol. 2004;15(6):566–569. doi: 10.1111/j.1399-3038.2004.00158.x
  42. Barannik VA. Clinical and biochemical rationale for the correction of vitamin deficiency in children with atopic dermatitis [dissertation abstract]. Moscow; 2008. 29 р. (In Russ).
  43. Food allergy. Clinical guidelines. Moscow: Russian Union of Pediatricians; 2018. 50 p. (In Russ).
  44. Meyer R, de Koker C, Dziubak R, et al. Dietary elimination of children with food protein induced gastrointestinal allergy ― micronutrient adequacy with and without a hypoallergenic formula? Clin Transl Allergy. 2014;4(1):31. doi: 10.1186/2045-7022-4-31
  45. Boaventura RM, Mendonça RB, Fonseca FA, et al. Nutritional status and food intake of children with cow’s milk allergy. Allergol Immunopathol (Madr). 2019;47(6):544–550. doi: 10.1016/j.aller.2019.03.003
  46. Oren E, Banerji A, Camargo CA. Vitamin D and atopic disorders in an obese population screened for vitamin D deficiency. J Allergy Clin Immunol. 2008;121(2):533–534. doi: 10.1016/j.jaci.2007.11.005
  47. Di Filippo P, Scaparrotta A, Rapino D, et al. Vitamin D supplementation modulates the immune system and improves atopic dermatitis in children. Int Arch Allergy Immunol. 2015; 166(2):91–96. doi: 10.1159/000371350
  48. Wang SS, Hon KL, Kong AP, et al. Vitamin D deficiency is associated with diagnosis and severity of childhood atopic dermatitis. Pediatr Allergy Immunol. 2014;25(1):30–35. doi: 10.1111/pai.12167
  49. Baek JH, Shin YH, Chung IH, et al. The link between serum vitamin D level, sensitization to food allergens, and the severity of atopic dermatitis in infancy. J Pediatr. 2014;165(4):849–54.e1. doi: 10.1016/j.jpeds.2014.06.058
  50. Fissinger A, Mages KC, Solomon AB. Vitamin deficiencies in pediatric eosinophilic esophagitis: a systematic review. Pediatr Allergy Immunol. 2020;31(7):835–840. doi: 10.1111/pai.13297
  51. Paassilta M, Kuusela E, Korppi M, et al. Food allergy in small children carries a risk of essential fatty acid deficiency, as detected by elevated serum mead acid proportion of total fatty acids. Lipids Health Dis. 2014;13:180. doi: 10.1186/1476-511X-13-180
  52. Bjerraggrd P, Mulvad G. The best of two worlds: how the Greenland Board of Nutrition has handled conflicting evidence about diet and health. Int J Circumpolar Health. 2012;71:18588. doi: 10.3402/ijch.v71i0.18588
  53. Miles EA, Calder PC. Can early omega-3 fatty acid exposure reduce risk of childhood allergic disease? Nutrients. 2017;9(7):784. doi: 10.3390/nu9070784
  54. Russel FD, Burgin-Maunder CS. Distinguishing health benefits of eicosapentaenoic and docosahexaenoic acids. Mar Drugs. 2012;10(11):2535–2559. doi: 10.3390/md10112535
  55. Arterburn LM, Oken HA, Bailey Hall E, et al. Algal-oil capsules and cooked salmon: nutritionally equivalent sources of docosahexaenoic acid. Am Diet Assoc. 2008;108(7):1204–1209. doi: 10.1016/j.jada.2008.04.020
  56. Tur J, Bibiloni M, Sureda A, Pons A. Dietary sources of omega 3 fatty acids: public health risks and benefits. Br J Nutr. 2012;107(Suppl 2):S23–S52. doi: 10.1017/S0007114512001456
  57. Meyer R, de Koker C, Dziubak R, et al. A practical approach to vitamin and mineral supplementation in food allergic children. Clin Transl Allergy. 2015;5(11):10. doi: 10.1186/s13601-015-0054-y
  58. Ladodo KS, Borovik TE, Makarova SG, et al. The nutritional prophylaxis of anemia and hypovitaminosis in children with allergic diseases. Pediatric Pharmacology. 2006;3(3):62–64. (In Russ). doi: 10.15690/pf.v12i5.1459

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