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Assessment of Rosaceae sensitisation diagnostics in allergic children
- Authors: Pampura AN1, Konjukova NG1, Fedenko ES2, Havkin AI1, Okuneva TS1
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Affiliations:
- Moscow Research Institute of Pediatric and Child Surgery
- Institute of Immunology
- Issue: Vol 9, No 1 (2012)
- Pages: 66-72
- Section: Articles
- URL: https://rusalljournal.ru/raj/article/view/732
- DOI: https://doi.org/10.36691/RJA732
- ID: 732
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Abstract
Background. Sensitization to the fruits of the family Rosaceae is widespread in children population, but its diagnostics is often difficult. Methods. The study included 190 children with suspected allergy to the fruit family of Rosaceae. Results. The presence of sensitization was found in 148 patients. Qualitatively, the results of in vitro and in vivo tests with allergens differed approximately one third of cases. Among children with sensitization to the fruits of a family Rosaceae specific IgE to rBet v 1 was identified approximately in 3/4, rPru p 3 — in 2/3, rBet v 2 — in 1/5 of patients. Conclusion. The results indicate a high informative determination of specific IgE (ImmunoCap, Phadia AB) to the fruits of Rosaceae (apple, pear, peach) and a recombinant allergens (rBet v 1, rBet v 2, rPru p 3).
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About the authors
A N Pampura
Moscow Research Institute of Pediatric and Child Surgery
Email: apampura@pedklin.ru
Russia
N G Konjukova
Moscow Research Institute of Pediatric and Child SurgeryRussia
E S Fedenko
Institute of ImmunologyMoskow, Russia
A I Havkin
Moscow Research Institute of Pediatric and Child SurgeryRussia
T S Okuneva
Moscow Research Institute of Pediatric and Child SurgeryRussia
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