βDEFENZINY: SVOYSTVA I FUNKTsII



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Abstract

Продукция природных катионных пептидов - важный механизм врожденного иммунитета человека.
βДефензины человека принадлежат семейству катионных трисульфидсодержащих микробоцидных
пептидов. Кроме прямых антимикробных функций, βдефензины играют множественную роль как ме
диаторы воспаления, влияют на хемотаксис, обладают иммуномодулирующей, цитотоксической и др.
активностями. Более того, βдефензины рассматриваются как лекарства нового поколения, которые мож
но будет использовать как антибактериальные средства, как модуляторы воспаления и при терапии рака.
Кроме того, βдефензины играют важную воль в аутоиммунных патологиях

About the authors

A S Budikhina

B V Pinegin

References

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