Age dependence on the clinical signs frequency of the immune system dysfunction amongthe personnel of Mountain-chemical plant in Krasnoyarsk region, according to monitoringin2007-2008

Background. Improvement of the specialized allergological and immunological care to the personnel of Mountain-chemical plant (MCP) in Krasnoyarsk region and population living in the area of its placing. Methods. The analysis of age occurrence of clinical symptoms of the dysfunction of immune system by results of specialized clinical, immunological and allergological evaluations during spring - autumn of 2007 and spring of 2008 is carried out. 765 persons from the personnel of MCP and 185 persons of the population from the area around were examined. The analysis of dynamics of clinical symptoms of immune dysfunction in MCP personnel and the population was performed in age groups: before 30 years, 30-39 years, 40-49 years, 50-59 years, 60 years and more .
Results. The general frequency of clinical symptoms of dysfunction of immune system in MCP personnel had no significant differences between age groups but in all groups of the personnel at the age of 30-60 years was significantly lower, in comparison with the population (p<0,05). Significantly lower was the frequency of ENT infections - at the age of 50 years and more senior, frequent ARVI in age groups 30-49 years old, a simple herpes in 40-49 years (p<0,05). Frequency of recurrent urticaria at the age before 30 years and 50-59 years was lower. At the age of 30-39 years frequency of atopic bronchial asthma was lower.
Conclusion. Differences in age dynamics of frequency of occurrence of clinical symptoms of immune dysfunction between the personnel and the population are established.

Mountain-chemical plant, clinical signs, dysfunction of immune system, personnel, age, dynamics