Lavrova O.V., Dymarskaya Y.R., Petrova M.A., Fedoseev G.B. To the question of prenatal predisposing factors to allergic diseases

· RAJ №1-2016

Lavrova O.V., Dymarskaya Y.R., Petrova M.A., Fedoseev G.B.

Pavlov`s First Saint-Petersburg State Medical University, Russia

Key words: asthma, pregnancy, children, allergy

Background. To study the peculiarities of pregnancy in asthma women and the health status of their children.
Materials and methods. We examined the natural course and outcomes of pregnancy of 1010 women with asthma
and monitored health status of their children up to 7 years old. Women were under the observation of pulmonologist
and obstetrician throughout the period of gestation; they were treated if necessary and provided with
recommendations for the primary prevention of allergic diseases in unborn child. Immediately after delivery
children were under the supervision of a pediatrician, allergist.
Results. Rising incidence of pregnancy complications in patients with asthma is directly related to the lack of
control of the disease, especially in the first trimester of gestation. The lack of adequate treatment of asthma
increases the risk of threatened abortion (OR 1,76, CI 0,90–3,47), preeclampsia (OR 2,77, CI 0,94–8,14), placental
insufficiency (OR 2,45, CI 1,04–5,87), which has a direct effect on the formation of allergic diseases and, particularly,
asthma in their children.
Conclusion. Even severe asthma, is not a contraindication for pregnancy. The basic condition for the safety
pregnancy and delivery is the adequate medical care that is a set of preventive and therapeutic measures for
control of the disease that improve the quality of life of women during gestation and reduce the risk of allergic
disease in their children.