Elisyutina O.G., Shtyrbul O.V., Zemskaya E.N. The correction of epidermal barrier dysfunction in atopic dermatitis patients

· RAJ №3-2016

Elisyutina O.G., Shtyrbul O.V., Zemskaya E.N.

Institute of Immunology, Moscow, Russia

Key words: atopic dermatitis, epidermal barrier, epidermis lipids, Сetaphil® RESTORADERM™

Atopic dermatitis is chronic inflammatory multifactorial disease, which has genetic disorders, immune mechanisms
of development and is under the ainfluence of a combination of exogenous and endogenous factors. Recently a
leading role of the epidermal barrier dysfunction in the pathogenesis of atopic dermatitis was shown. The article
presents data about emollient for skin care efficacy – Cetaphil® RESTORADERM, which consists of preceramides
and filaggrin breakdown products in complex treatment of atopic dermatitis patients.